Short answer
Word and InDesign are useful for producing isolated documents, but they reach their limits when an organization must maintain many content sets, variants, languages, and formats. Copy-paste creates errors, versions diverge, and updates become manual.
Calenco works as a CCMS: content is structured into reusable modules, approved through workflows, translated in sync, and published automatically according to the company's brand rules.
The difference is clearest during maintenance. Updating information in Calenco can update every relevant publication, while Word or InDesign files often need to be corrected, checked, and laid out one by one.